Health & Beauty

"In 2021, 12 new Chinese medicine drugs (including 9 innovative drugs) will be approved for marketing, and 34 Chinese medicine clinical trials will be approved, which is the year with the largest number of new Chinese medicine drugs and clinical trials in the past five years." At the National Traditional Chinese Medicine Scientific Supervision Conference hosted by China Health Media Group, Zhao Junning, deputy director of the State Food and Drug Administration, revealed.

Chinese medicine is the treasure of Chinese civilization, and Chinese medicine is the cornerstone of the development of Chinese medicine. In the battle against the new crown epidemic, which is closely linked with the virus, traditional Chinese medicine shines brightly.

However, it is undeniable that although the theory of traditional Chinese medicine in my country is advanced, the modernization of traditional Chinese medicine is still in its infancy, and the production technology is backward. Problems such as the quality of medicinal materials and rough craftsmanship have made traditional Chinese medicine criticized for a long time. How to keep upright and innovate and effectively promote the high-quality development of traditional Chinese medicine has become the focus of the participants.

The basic research of traditional Chinese medicine needs to be strengthened urgently

"At present, outstanding progress has been made in the creation of new Chinese medicines in my country, and the number of new Chinese medicines on the market has increased from 2 in 2018 to 20 in 2021. Innovative medicines mulberry total alkaloid tablets, icariin soft capsules (acoladine) It has completely independent intellectual property rights." Speaking of these, Chen Kaixian, an academician of the Chinese Academy of Sciences, is quite proud.

Chen Kaixian said that Chinese medicine has unique advantages for complex diseases such as major and difficult diseases, chronic diseases, and senile diseases. Using modern technology to conduct in-depth research and develop new traditional Chinese medicines on the basis of clarifying their active ingredients and mechanisms of action is the advantage of my country's new drug research and development.

In recent years, the level of secondary development of traditional Chinese medicine in my country has been significantly improved, and a number of enterprises and products with market competitiveness have emerged. "However, in the process of moving towards the intelligent production of traditional Chinese medicine, there are still some technical bottlenecks to be broken through, such as the lack of upstream and downstream coordination and integration of the industrial chain, and many technological difficulties still require human intervention. Larger distance." Chen Kaixian emphasized.

Chen Kaixian believes that in order to realize the modernization of traditional Chinese medicine, we must firmly grasp the three fundamental systems of "traditional Chinese medicine resources, traditional Chinese medicine quality, and clinical efficacy", continue to strengthen the original theoretical research of traditional Chinese medicine such as nature, flavor, meridian, compatibility, etc. It is necessary to carry out in-depth research on the objective evaluation of the efficacy of traditional Chinese medicine, from the perspective of the combination of basic and clinical, to solve the problem of evaluation of the efficacy of traditional Chinese medicine, and to evidence the efficacy of traditional Chinese medicine.

"At present, no major breakthrough has been made in the core issues such as the analysis of the medicinal properties and complex effects of traditional Chinese medicine, and there is still a lack of consensus on the evaluation and confirmation of the efficacy of traditional Chinese medicine. It is urgent to strengthen basic research on traditional Chinese medicine." Chen Kaixian said.

The enlightenment of artemisinin to the modernization of traditional Chinese medicine

"The artemisinin model can be learned from the modernization of traditional Chinese medicine." At the scene, Huang Luqi, an academician of the Chinese Academy of Engineering, caught the attention of the participants as soon as he spoke.

Huang Luqi explained that the artemisinin model clarified how to select topics, who will organize, and how to organize. First of all, the artemisinin project was proposed under the background that the country and the world are facing the problem of malaria infection. Secondly, artemisinin has become a new generation of antimalarial drugs, which is the result of joint efforts from both inside and outside the industry and the joint efforts of all parties. At the same time, to promote the modernization of traditional Chinese medicine, it is necessary to grasp the importance of inheriting the essence, and achieve internal understanding and inheritance.

"Similarly, the modernization of traditional Chinese medicine should also use the power of the whole country to answer the key scientific questions of traditional Chinese medicine, facing the frontier of world science and technology, facing the major needs of the country, facing the people's health, and facing the main battlefield of the economy." Huang Luqi said, such as targeting the pathogenesis of traditional Chinese medicine , medicinal properties, efficacy and other key scientific issues are unclear, and the modern theory of meridians and acupoints still needs to be systematized. Strengthen the in-depth integration of multidisciplinary cutting-edge technologies and traditional Chinese medicine, and promote theoretical innovation and practical application of traditional Chinese medicine. understand" its scientific connotation.

Zhao Junning said that to promote the innovation and development of traditional Chinese medicine, supervision should also keep pace with the times, and accelerate the construction of a review and approval system that conforms to the characteristics of traditional Chinese medicine. "The most significant change is to promote the construction of a traditional Chinese medicine registration review evidence system that combines traditional Chinese medicine theory, human experience, and clinical trials, and to break the evaluation method of 'in Western medicine'."

In Chen Kaixian's view, the exact curative effect is the foundation and lifeline for the survival and development of traditional Chinese medicine, and it is also one of the key issues in the modernization and innovation of traditional Chinese medicine. "On the basis of learning from the evidence-based medicine concept of modern medicine and respecting the laws of traditional Chinese medicine, we should innovate the evaluation methods and techniques of traditional Chinese medicine, organically combine the advantages and characteristics of traditional Chinese medicine with the benefits of patients, and establish a clinical evaluation recognized at home and abroad. method, and provide a scientific basis for the rational clinical application of traditional Chinese medicine." Chen Kaixian said.